Ted Lilly started his career in 1999 with the Montreal Expos. He made his first major league start on September 19, against the Atlanta Braves. He got traded to the New York Yankees on March 17,2000 for Hideki Irabu. In 2002, he got traded to the Oakland Athletics, which also involved, Tigers Jeff Weaver to the New York Yankees, and Athletics Jemery Bonderman to the Tigers. He pitched for the A's in the division series in both 2002 and 2003.
He got traded to the Toronto Blue Jays in 2004 for Bobby Kiety. He also made to the All-Star-Game that same year too. He got kicked out of a game against one of his former teams the Oakland Athletics in 2006. He joined the Chicago Cubs on December 6,2006. He made to the All-Star-Game in 2009. He lost a no-hitter on June 13,2010 against the Chicago White Sox. Later on July 31, that year he and Ryan Theriot got traded to the Los Angeles Dodgers for Blake DeWitt.